Tirzepatide is a once-weekly subcutaneous injectable peptide approved by the FDA for type 2 diabetes. It is a unique medication that mimics two hormones naturally found in the body: GLP-1 and GIP. When used along with diet and lifestyle changes, tirzepatide helps with weight loss by slowing down how fast food travels through your digestive tract (called gastric emptying) decreasing appetite, food cravings and food intake. It increases fat burning including visceral fat.
Semaglutide is a glucagon-like peptide-1 (GLP-1) agonist. GLP-1 is a natural hormone in your body that acts on your brain to regulate your appetite and food intake. By acting like GLP-1, semaglutide lowers your appetite and how much food you eat to help manage your weight. This weekly injection is used together with diet and exercise to help control your blood sugar. This medicine is also used to lower the risk of heart attack, stroke, or death in patients with type 2 diabetes.